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PUBLICATIONS

The PROTEOSTEM lab is led by Dr. William Grey at the University of York.

We focus on the role of protein homeostasis – so called “Proteostasis” – in healthy and malignant stem cell development.
The predominant focus of the lab is the haematopoietic (blood) system and cancerous transformation to acute myeloid leukaemia (AML).

RECENT PUBLICATIONS

Rix et al. (2025) NPJ Precision Oncology

Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer

Rix et al. (2025) NPJ Precision Oncology

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Miranda et al. (2025) Exp. Haem.

Ex vivo modelling reveals low levels of CKS1 inhibition boost haematopoiesis via AKT/Foxo1 signalling

Miranda et al. (2025) Exp. Haem.

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Bahou et al. (2023) Biomacromolecules

Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones

Bahou et al. (2023) Biomacromolecules

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FUNDERS

We thank all our funders, patients and advocates for supporting work in the ProteoStem lab.

The ProteoStem lab is supported by the following grants:

Medical Research Council Career Development Award.

John Goldman Fellowship from Leukaemia U.K.

European Haematology Association Bilateral Collaborative Grant

Children’s Cancer and Leukaemia Group Little Princess Trust Grant

National Mouse Genetics Network (MRC) Director’s Award.

Clinical Academic Research Partnership (MRC) Award.

Lady Tata Memorial Trust Grant

The British Society of Haematology